Duncanson didn’t only find discord in Cincinnati. He also engaged with the city’s dedicated abolitionist community. James Birney was publishing his abolitionist newspaper The Philanthropist, despite his printing press being destroyed twice by pro-slavery Cincinnatians. Duncanson met James Presley Ball, an African American photographer who owned a flourishing business; he hand-colored photographs in Ball’s studio, exhibited his paintings in Ball’s gallery, and collaborated with Ball to create a panorama illustrating the history of slavery in the United States. Frederick Douglass visited Cincinnati several times, and it is possible that Duncanson heard him speak or perhaps even met him (Ball photographed Douglass in Cincinnati in 1867).
In 1852, the year Duncanson finished the murals, Harriet Beecher Stowe’s Uncle Tom’s Cabin was published, largely inspired by her earlier experiences in Cincinnati. One year later, Duncanson painted Uncle Tom and Little Eva, which depicted a scene from the novel. He also completed portraits of abolitionists, donated paintings to the cause, participated in protests, and attended anti-slavery lectures. Although existing documents connecting Nicholas Longworth to abolition are scarce, commissioning such an ambitious mural project for his own home from a young Black artist would have sent a message. Longworth provided additional professional support for Duncanson, helping fund the artist’s first journey to Europe and providing a letter of introduction to fellow Cincinnatian Hiram Powers, a sculptor who had already established a studio in Florence, Italy. Longworth called Duncanson “a man of great industry and worth.”